IL-17 modulator 1 disodium

• CAT Number: I045269
• CAS Number: 2446803-91-2
• Molecular Formula: C28H35N6Na2O6P
• Molecular Weight: 628.57
• Purity: ≥95%
• Synonyms: disodium;[4-[4-[[(2S)-3,3-dicyclopropyl-2-[(2-propan-2-ylpyrazole-3-carbonyl)amino]propanoyl]amino]phenyl]-3,5-dimethylpyrazol-1-yl]methyl phosphate
• InChI: InChI=1S/C28H37N6O6P.2Na/c1-16(2)34-23(13-14-29-34)27(35)31-26(25(20-5-6-20)21-7-8-21)28(36)30-22-11-9-19(10-12-22)24-17(3)32-33(18(24)4)15-40-41(37,38)39;;/h9-14,16,20-21,25-26H,5-8,15H2,1-4H3,(H,30,36)(H,31,35)(H2,37,38,39);;/q;2*+1/p-2/t26-;;/m0../s1
• InChIKey: PMFLGFBTYONBAO-ROPHLPQBSA-L
• SMILES: CC1=C(C(=NN1COP(=O)([O-])[O-])C)C2=CC=C(C=C2)NC(=O)[C@H](C(C3CC3)C4CC4)NC(=O)C5=CC=NN5C(C)C.[Na+].[Na+]

IL-17 Modulator 1 disodium（Cat No.:I045269）is a small-molecule compound that modulates interleukin-17 (IL-17) signaling, a key pathway in autoimmune and inflammatory diseases. By regulating IL-17–mediated activation of downstream cascades such as NF-κB and MAPK, it reduces pro-inflammatory cytokine and chemokine production. The disodium salt form offers improved solubility for experimental applications. This compound is valuable for studying IL-17–driven conditions, including psoriasis, rheumatoid arthritis, ankylosing spondylitis, and other chronic inflammatory disorders. Its potency, selectivity, and compatibility with cell-based and in vivo studies make it a useful tool for cytokine-targeted therapeutic research.