For research use only. Not for therapeutic Use.
IGF1-LR3 (Cat No.:P000426) is a synthetic analog of human IGF-1, engineered for enhanced stability and bioactivity. It differs from native IGF-1 by a substitution of arginine for glutamic acid at position 3 and an extended N-terminal, which significantly reduces its binding to IGF-binding proteins, prolonging its half-life and increasing its potency. IGF1-LR3 promotes cell growth, muscle development, and protein synthesis, making it valuable in biomedical research and regenerative studies. It is commonly used in cell culture and tissue engineering to stimulate cellular proliferation and recovery.
| CAS Number | 946870-92-4 |
| Synonyms | Long arginine 3-IGF-1 |
| Molecular Formula | C400H625N111O115S9 |
| Purity | ≥95% |
| IUPAC Name | 2-[4-[2-[3-[bis(2-hydroxyoctadeca-9,12-dienyl)amino]propyldisulfanyl]ethyl]piperazin-1-yl]ethyl 5-[bis(2-hydroxytetradecyl)amino]pentanoate |
| InChI | InChI=1S/C80H154N4O6S2/c1-5-9-13-17-21-25-29-31-33-35-39-43-47-51-58-78(87)74-84(75-79(88)59-52-48-44-40-36-34-32-30-26-22-18-14-10-6-2)62-55-70-91-92-71-68-82-65-63-81(64-66-82)67-69-90-80(89)60-53-54-61-83(72-76(85)56-49-45-41-37-27-23-19-15-11-7-3)73-77(86)57-50-46-42-38-28-24-20-16-12-8-4/h21-22,25-26,31-34,76-79,85-88H,5-20,23-24,27-30,35-75H2,1-4H3 |
| InChIKey | CRZOPHSORDIMRX-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCC(CN(CCCCC(=O)OCCN1CCN(CC1)CCSSCCCN(CC(CCCCCCC=CCC=CCCCCC)O)CC(CCCCCCC=CCC=CCCCCC)O)CC(CCCCCCCCCCCC)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
