For research use only. Not for therapeutic Use.
Iferanserin(CAT: I007268) is a selective serotonin 5-HT₂A receptor antagonist developed for the treatment of vascular and gastrointestinal disorders. By blocking 5-HT₂A–mediated vasoconstriction and platelet aggregation, it has been investigated as a topical therapy for hemorrhoidal disease, where it demonstrated efficacy in reducing bleeding and improving symptoms. Iferanserin’s pharmacological profile also makes it a useful tool in research exploring serotonin receptor signaling, vascular biology, and hemostasis. Its selective antagonism provides researchers with a means to dissect the role of 5-HT₂A pathways in thrombosis, vascular tone regulation, and inflammatory processes relevant to gastrointestinal and cardiovascular research.
| CAS Number | 58754-46-4 |
| Synonyms | (E)-N-[2-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]phenyl]-3-phenylprop-2-enamide |
| Molecular Formula | C23H28N2O |
| Purity | ≥95% |
| IUPAC Name | (E)-N-[2-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]phenyl]-3-phenylprop-2-enamide |
| InChI | InChI=1S/C23H28N2O/c1-25-18-8-7-12-21(25)16-15-20-11-5-6-13-22(20)24-23(26)17-14-19-9-3-2-4-10-19/h2-6,9-11,13-14,17,21H,7-8,12,15-16,18H2,1H3,(H,24,26)/b17-14+/t21-/m0/s1 |
| InChIKey | UXIPFQUBOVWAQW-UEBLJOKOSA-N |
| SMILES | CN1CCCCC1CCC2=CC=CC=C2NC(=O)C=CC3=CC=CC=C3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
