For research use only. Not for therapeutic Use.
IDT307 (Cat No.: I012823) is a fluorescent dye derivative of rhodamine used as a substrate for vesicular monoamine transporters (VMATs), particularly VMAT2. It is taken up into synaptic vesicles in a transporter-dependent manner, allowing researchers to monitor vesicular loading and neurotransmitter storage in live cells. Upon accumulation, IDT307 exhibits strong fluorescence, enabling real-time imaging of vesicular trafficking and function. It is widely used in neuroscience and pharmacology to study monoamine transport, synaptic vesicle dynamics, and the effects of drugs on neurotransmitter storage and release.
CAS Number | 1141-41-9 |
Synonyms | N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline;iodide |
Molecular Formula | C14H17IN2 |
Purity | ≥95% |
InChI | InChI=1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1 |
InChIKey | CAMWVBRDIKKGII-UHFFFAOYSA-M |
SMILES | C[N+]1=CC=C(C=C1)C2=CC=C(C=C2)N(C)C.[I-] |
Reference | [1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018. |
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