ICG-carboxylic acid

• CAT Number: I044730
• CAS Number: 181934-09-8
• Molecular Formula: C45H50N2O5S
• Molecular Weight: 730.95
• Purity: ≥95%
• Synonyms: 6-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]hexanoate
• IUPAC Name: 4-[(2Z)-2-[(2E,4E,6E)-7-[3-(5-carboxypentyl)-1,1-dimethylbenzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate
• InChI: InChI=1S/C45H50N2O5S/c1-44(2)39(46(30-16-8-11-25-41(48)49)37-28-26-33-19-12-14-21-35(33)42(37)44)23-9-6-5-7-10-24-40-45(3,4)43-36-22-15-13-20-34(36)27-29-38(43)47(40)31-17-18-32-53(50,51)52/h5-7,9-10,12-15,19-24,26-29H,8,11,16-18,25,30-32H2,1-4H3,(H-,48,49,50,51,52)
• InChIKey: HIBVKROMGIHYKL-UHFFFAOYSA-N
• SMILES: CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCCC(=O)O)/C=C/C=C/C=C/C=C\4/C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C

ICG-carboxylic acid（Cat No.:I044730）is a functional derivative of indocyanine green (ICG), a near-infrared (NIR) fluorescent dye widely used in biomedical imaging. The addition of a carboxylic acid group enables covalent conjugation to amine-containing molecules such as peptides, proteins, or nanoparticles via amide bond formation. ICG-carboxylic acid retains the strong NIR absorption and emission properties of native ICG, allowing for deep tissue imaging with minimal background interference. This compound is ideal for developing targeted imaging agents, fluorescence-guided surgery tools, and diagnostic probes, offering high biocompatibility and excellent optical performance in biological environments.