• CAT Number: I019193
  • CAS Number: 1690172-25-8
  • Molecular Formula: C₂₃H₂₆FN₅O₂
  • Molecular Weight: 423.48
  • Purity: ≥95%
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I-191(CAT: I019193) is a potent and selective antagonist of Protease-Activated Receptor 2 (PAR2), a G protein-coupled receptor that is involved in a variety of physiological and pathological processes, including inflammation, pain, and cancer. By inhibiting the activity of PAR2, I-191 can block the signaling pathways that lead to inflammation and pain. I-191 has shown promising results in preclinical studies as a potential therapy for inflammatory bowel disease, cancer, and other PAR2-mediated diseases. It has been found to reduce inflammation and tumor growth in animal models of these diseases. I-191 is currently undergoing further studies to evaluate its safety and efficacy in humans.

Catalog Number I019193
CAS Number 1690172-25-8
Molecular Formula


Purity 95%

[1]. Jiang Y, et al. A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells. J Pharmacol Exp Ther. 2018 Feb;364(2):246-257.

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