For research use only. Not for therapeutic Use.
Hypaconine(CAT: R035486) is a naturally occurring diterpenoid alkaloid isolated from plants of the Aconitum genus (Ranunculaceae family). Structurally related to aconitine-type alkaloids, hypaconine has been studied for its analgesic, anti-inflammatory, and cardiotonic properties, though it also exhibits notable toxicity. Research suggests it can modulate voltage-gated sodium channels, influencing nerve conduction and cardiac excitability. Due to its potent bioactivity, hypaconine is often investigated in the context of traditional herbal medicine, toxicology, and pharmacology. It serves as an important reference compound for exploring the pharmacological mechanisms and safety profiles of aconite-derived alkaloids in both therapeutic and toxicological studies.
| CAS Number | 63238-68-6 |
| Synonyms | (2R,3R,4R,5R,6S,7S,8R,13S,16S,17R,18R)-6,16,18-trimethoxy-13-(methoxymethyl)-11-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,5,7,8-tetrol |
| Molecular Formula | C24H39NO8 |
| Purity | ≥95% |
| IUPAC Name | (2R,3R,4R,5R,6S,7S,8R,13S,16S,17R,18R)-6,16,18-trimethoxy-13-(methoxymethyl)-11-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,5,7,8-tetrol |
| InChI | InChI=1S/C24H39NO8/c1-25-9-21(10-30-2)7-6-12(31-3)23-11-8-22(28)18(26)13(11)24(29,19(27)20(22)33-5)14(17(23)25)15(32-4)16(21)23/h11-20,26-29H,6-10H2,1-5H3/t11-,12+,13-,14?,15+,16-,17?,18-,19+,20+,21+,22-,23?,24-/m1/s1 |
| InChIKey | BQTYHFZQSAKNQU-YGJBFQRCSA-N |
| SMILES | CN1CC2(CCC(C34C2C(C(C31)C5(C6C4CC(C6O)(C(C5O)OC)O)O)OC)OC)COC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
