hydroxymethyldeoxyuridine triphosphate

• CAT Number: M052667
• CAS Number: 14167-70-5
• Molecular Formula: C10H17N2O15P3
• Molecular Weight: 498.17
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: [hydroxy-[[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxopyrimidin-1-yl]oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate
• InChI: InChI=1S/C10H17N2O15P3/c13-3-5-2-12(10(16)11-9(5)15)8-1-6(14)7(25-8)4-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,6-8,13-14H,1,3-4H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t6-,7+,8+/m0/s1
• InChIKey: RLHFVRMIEVOHOR-XLPZGREQSA-N
• SMILES: C1C(C(OC1N2C=C(C(=O)NC2=O)CO)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

Hydroxymethyldeoxyuridine triphosphate (Cat No.: 052667) is a modified nucleotide analog of deoxyuridine triphosphate (dUTP), in which a hydroxymethyl group is attached to the uracil base. It is primarily used in molecular biology and epigenetics research, particularly in DNA labeling, replication studies, and the synthesis of modified DNA strands. This compound can be enzymatically incorporated into DNA by polymerases, allowing for detection, structural analysis, or further chemical modification. hm-dUTP is valuable in studying DNA-protein interactions, methylation effects, and developing diagnostic or therapeutic tools.