<p>
<span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">Hydroxy Varenicline (CAS 357424-21-6) is a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline.</span></span></p>
| Catalog Number | R009114 |
| CAS Number | 357424-21-6 |
| Synonyms | 1,6,7,8,9,10-Hexahydro-6,10-methano-2H-pyrazino[2,3-h][3]benzazepin-2-one; |
| Molecular Formula | C13H13N3O |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4(9),7,10-tetraen-6-one |
| InChI | InChI=1S/C13H13N3O/c17-13-6-15-11-2-9-7-1-8(5-14-4-7)10(9)3-12(11)16-13/h2-3,6-8,14H,1,4-5H2,(H,16,17) |
| InChIKey | GKJIHIDMYKLTHW-UHFFFAOYSA-N |
| SMILES | C1C2CNCC1C3=CC4=C(C=C23)NC(=O)C=N4 |
| Reference | <span style="color:#000000;"><span style="font-size:12px;"><span style="font-family:arial,helvetica,sans-serif;">1.Obach, R. Scott, et al. "Metabolism and disposition of varenicline, a selective α4β2 acetylcholine receptor partial agonist, in vivo and in vitro." <i style="font-family: Arial, sans-serif; font-size: 13px;">Drug metabolism and disposition</i> 34.1 (2006): 121-130.</span></span></span> |
