For research use only. Not for therapeutic Use.
Hydroxy-PEG5-acid (Cat No.: I028997) is a polyethylene glycol (PEG)-based linker molecule containing five ethylene glycol units with a terminal hydroxyl group on one end and a carboxylic acid group on the other. This bifunctional structure enables its use in bioconjugation, drug delivery, and surface modification applications. The PEG backbone imparts water solubility, flexibility, and biocompatibility, reducing immunogenicity and enhancing circulation time in vivo. Hydroxy-PEG5-acid is widely utilized in the synthesis of PEGylated biomolecules, nanoparticles, and hydrogels for biomedical and pharmaceutical research.
| CAS Number | 2079768-50-4 |
| Synonyms | 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Molecular Formula | C13H26O8 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H26O8/c14-2-4-18-6-8-20-10-12-21-11-9-19-7-5-17-3-1-13(15)16/h14H,1-12H2,(H,15,16) |
| InChIKey | NQZLSNLBIKBFNP-UHFFFAOYSA-N |
| SMILES | C(COCCOCCOCCOCCOCCO)C(=O)O |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
