Hydroxy-PEG4-O-Boc

• CAT Number: I016586
• CAS Number: 1807530-05-7
• Molecular Formula: C16H32O8
• Molecular Weight: 352.42
• Purity: ≥95%
• Synonyms: tert-butyl 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetate
• InChI: InChI=1S/C16H32O8/c1-16(2,3)24-15(18)14-23-13-12-22-11-10-21-9-8-20-7-6-19-5-4-17/h17H,4-14H2,1-3H3
• InChIKey: XPLBSNFHNMATJJ-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)COCCOCCOCCOCCOCCO

Hydroxy-PEG4-O-Boc(CAT: I016586) is a polyethylene glycol (PEG) derivative containing four ethylene glycol units, a free hydroxyl group, and a tert-butoxycarbonyl (Boc)-protected terminal functionality. This bifunctional reagent is designed to serve as a versatile building block in organic synthesis and bioconjugation workflows. The PEG4 spacer imparts hydrophilicity, flexibility, and controlled molecular spacing, while the Boc group provides temporary protection for selective deprotection and further chemical modification. Researchers employ Hydroxy-PEG4-O-Boc in the design of linkers, drug conjugates, biomaterials, and surface coatings, where PEGylation improves solubility, reduces non-specific interactions, and enhances stability in biomedical and material science applications.