Hydroxy-PEG2-C2-methyl ester

• CAT Number: I016568
• CAS Number: 457897-73-3
• Molecular Formula: C8H16O5
• Molecular Weight: 192.21
• Purity: ≥95%
• Synonyms: methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
• InChI: InChI=1S/C8H16O5/c1-11-8(10)2-4-12-6-7-13-5-3-9/h9H,2-7H2,1H3
• InChIKey: ZWFWEUBKPURUHJ-UHFFFAOYSA-N
• SMILES: COC(=O)CCOCCOCCO

Hydroxy-PEG2-C2-methyl ester(CAT: I016568) is a bifunctional polyethylene glycol (PEG) derivative composed of two ethylene glycol units with a terminal hydroxyl group and a C2 methyl ester functionality. Its short PEG spacer provides controlled molecular flexibility, enhances hydrophilicity, and reduces steric hindrance, making it ideal for precise chemical modifications. The hydroxyl and ester groups serve as versatile reactive handles for conjugation and further derivatization. This reagent is widely employed in synthesis chemistry, drug delivery design, surface functionalization, and nanomaterial engineering. Its compact structure makes it especially useful where minimal PEG extension is required while maintaining solubility and stability.