For research use only. Not for therapeutic Use.
HX531（Cat No.:I006902）is a selective antagonist of retinoid X receptors (RXRs), nuclear receptors that regulate gene expression involved in metabolism, cell differentiation, and apoptosis. By inhibiting RXR-mediated transcriptional activity, HX531 modulates signaling pathways linked to insulin sensitivity, lipid metabolism, and cancer progression. It has been studied for its therapeutic potential in metabolic disorders such as type 2 diabetes and obesity, as well as in certain malignancies. HX531 is a valuable research tool for investigating RXR-dependent biological processes and evaluating the impact of RXR inhibition in metabolic and oncological disease models.
| CAS Number | 188844-34-0 |
| Synonyms | 4-(5,7,7,10,10-pentamethyl-2-nitro-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid |
| Molecular Formula | C29H29N3O4 |
| Purity | ≥95% |
| IUPAC Name | 4-(5,7,7,10,10-pentamethyl-2-nitro-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid |
| InChI | InChI=1S/C29H29N3O4/c1-28(2)12-13-29(3,4)22-16-25-20(15-21(22)28)26(17-6-8-18(9-7-17)27(33)34)30-23-14-19(32(35)36)10-11-24(23)31(25)5/h6-11,14-16H,12-13H2,1-5H3,(H,33,34) |
| InChIKey | SXKPGYKPQPYJER-UHFFFAOYSA-N |
| SMILES | CC1(CCC(C2=C1C=C3C(=C2)N(C4=C(C=C(C=C4)[N+](=O)[O-])N=C3C5=CC=C(C=C5)C(=O)O)C)(C)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
