For research use only. Not for therapeutic Use.
HTL14242（Cat No.:I007227）is a selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), a G-protein–coupled receptor involved in lipid sensing, glucose metabolism, and anti-inflammatory signaling. By activating FFA4, HTL14242 enhances insulin sensitivity, promotes glucose homeostasis, and modulates immune responses, making it highly valuable in metabolic and inflammatory disease research. Researchers use HTL14242 to study mechanisms underlying obesity, type 2 diabetes, and chronic inflammation, as well as the therapeutic potential of FFA4 modulation. Its specificity provides a robust tool for probing lipid–receptor interactions in metabolic regulation.
| CAS Number | 1644645-32-8 |
| Synonyms | 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile |
| Molecular Formula | C16H8ClFN4 |
| Purity | ≥95% |
| IUPAC Name | 3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile |
| InChI | InChI=1S/C16H8ClFN4/c17-12-4-10(7-19)3-11(5-12)15-6-16(22-9-21-15)14-2-1-13(18)8-20-14/h1-6,8-9H |
| InChIKey | FQAXDSVNYVVQSE-UHFFFAOYSA-N |
| SMILES | C1=CC(=NC=C1F)C2=CC(=NC=N2)C3=CC(=CC(=C3)C#N)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
