For research use only. Not for therapeutic Use.
HSP90-IN-27(CAT: I040545) is a potent and selective inhibitor of Heat Shock Protein 90 (HSP90), a molecular chaperone essential for the stability and function of numerous oncogenic client proteins. By disrupting HSP90’s ATPase activity, HSP90-IN-27 promotes degradation of client proteins involved in cell proliferation, survival, and stress response pathways. This inhibitor is especially valuable for investigating mechanisms of cancer progression, drug resistance, and proteostasis. HSP90-IN-27 is a powerful research tool for targeting HSP90-dependent signaling in tumor models and assessing the therapeutic potential of chaperone inhibition in oncology and neurodegenerative disease contexts. Suitable for in vitro biochemical and cellular assays.
| CAS Number | 525577-38-2 |
| Synonyms | N-methyl-N-[(1,3,5-trimethylpyrazol-4-yl)methyl]naphthalene-2-sulfonamide |
| Molecular Formula | C18H21N3O2S |
| Purity | ≥95% |
| IUPAC Name | N-methyl-N-[(1,3,5-trimethylpyrazol-4-yl)methyl]naphthalene-2-sulfonamide |
| InChI | InChI=1S/C18H21N3O2S/c1-13-18(14(2)21(4)19-13)12-20(3)24(22,23)17-10-9-15-7-5-6-8-16(15)11-17/h5-11H,12H2,1-4H3 |
| InChIKey | QQFAOBCJMZDGFZ-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=NN1C)C)CN(C)S(=O)(=O)C2=CC3=CC=CC=C3C=C2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
