hRIO2 kinase ligand-1

• CAT Number: I040541
• CAS Number: 923841-73-0
• Molecular Formula: C17H14N2O
• Molecular Weight: 262.31
• Purity: ≥95%
• Synonyms: 2-naphthalen-2-yl-N-pyridin-2-ylacetamide
• InChI: InChI=1S/C17H14N2O/c20-17(19-16-7-3-4-10-18-16)12-13-8-9-14-5-1-2-6-15(14)11-13/h1-11H,12H2,(H,18,19,20)
• InChIKey: KXZCFXKLOSDNKK-UHFFFAOYSA-N
• SMILES: C1=CC=C2C=C(C=CC2=C1)CC(=O)NC3=CC=CC=N3

hRIO2 Kinase Ligand-1(CAT: I040541) is a selective small-molecule ligand that targets human RIO2 kinase (hRIO2), an atypical serine/threonine kinase involved in ribosome biogenesis, cell cycle progression, and RNA processing. By binding to hRIO2, this compound provides a valuable chemical tool for probing its enzymatic activity and regulatory roles in cellular homeostasis and proliferation. hRIO2 Kinase Ligand-1 is especially useful for studying the function of RIO2 in cancer and other diseases where aberrant ribosome assembly and protein synthesis are implicated. Ideal for mechanistic investigations and early-stage drug discovery focused on nucleolar stress and translational control pathways.