HO-PEG10-CH2COOH

• CAT Number: I016281
• CAS Number: 2250056-53-0
• Molecular Formula: C22H44O13
• Molecular Weight: 516.58
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
• InChI: InChI=1S/C22H44O13/c23-1-2-26-3-4-27-5-6-28-7-8-29-9-10-30-11-12-31-13-14-32-15-16-33-17-18-34-19-20-35-21-22(24)25/h23H,1-21H2,(H,24,25)
• InChIKey: VEAWKHYVNPPKRE-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)O)O

HO-PEG10-CH2COOH(CAT: I016281) is a heterobifunctional polyethylene glycol (PEG) derivative with a terminal hydroxyl group on one end and a carboxymethyl group on the other. The PEG10 spacer, composed of ten ethylene glycol units, provides flexibility, hydrophilicity, and excellent solubility in aqueous and organic solvents. The hydroxyl group serves as a versatile handle for further chemical modification, while the carboxylic acid can be activated to form amide or ester linkages with nucleophiles such as amines or alcohols. This reagent is commonly employed in bioconjugation, polymer chemistry, drug delivery, and surface functionalization, where medium-length PEG linkers enhance stability and reduce steric hindrance.