hnRNPK-IN-1

• CAT Number: I044515
• CAS Number: 2313528-04-8
• Molecular Formula: C23H21N3O5
• Molecular Weight: 419.43
• Purity: ≥95%
• Synonyms: (E)-1-(4-methoxyphenyl)-3-(4-morpholin-4-yl-6-nitroquinolin-2-yl)prop-2-en-1-one
• InChI: InChI=1S/C23H21N3O5/c1-30-19-6-2-16(3-7-19)23(27)9-4-17-14-22(25-10-12-31-13-11-25)20-15-18(26(28)29)5-8-21(20)24-17/h2-9,14-15H,10-13H2,1H3/b9-4+
• InChIKey: PFTIJUIEMIEMQH-RUDMXATFSA-N
• SMILES: COC1=CC=C(C=C1)C(=O)/C=C/C2=CC(=C3C=C(C=CC3=N2)[N+](=O)[O-])N4CCOCC4

hnRNPK-IN-1（Cat No.:I044515）is a selective small-molecule inhibitor targeting heterogeneous nuclear ribonucleoprotein K (hnRNPK), a multifunctional RNA-binding protein involved in transcriptional regulation, RNA processing, and signal transduction. hnRNPK is implicated in various cancers due to its role in regulating oncogene expression, cell cycle progression, and apoptosis. By inhibiting hnRNPK activity, hnRNPK-IN-1 disrupts its interaction with nucleic acids and associated protein complexes, leading to modulation of gene expression and suppression of tumor cell viability. This compound serves as a valuable tool in cancer research and molecular biology for investigating hnRNPK’s role in gene regulation and disease progression.