hMC1R agonist 1

• CAT Number: I043949
• CAS Number: 3028881-87-7
• Molecular Formula: C54H70N14O8S2
• Molecular Weight: 1107.35
• Purity: ≥95%
• Synonyms: (5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
• InChI: InChI=1S/C54H70N14O8S2/c1-3-4-17-40(62-32(2)69)48(71)68-46-30-78-28-35-15-10-14-34(21-35)27-77-29-45(47(55)70)67-51(74)43(23-36-25-60-39-18-9-8-16-38(36)39)65-49(72)41(19-11-20-59-54(56)57)63-50(73)42(22-33-12-6-5-7-13-33)64-52(75)44(66-53(46)76)24-37-26-58-31-61-37/h5-10,12-16,18,21,25-26,31,40-46,60H,3-4,11,17,19-20,22-24,27-30H2,1-2H3,(H2,55,70)(H,58,61)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)(H,68,71)(H4,56,57,59)/t40-,41-,42+,43-,44-,45-,46-/m0/s1
• InChIKey: YBWGYSWBATYFBD-RQTVHLMQSA-N
• SMILES: CCCC[C@@H](C(=O)N[C@H]1CSCC2=CC(=CC=C2)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CC3=CN=CN3)CC4=CC=CC=C4)CCCN=C(N)N)CC5=CNC6=CC=CC=C65)C(=O)N)NC(=O)C

hMC1R Agonist 1（Cat No.:I043949）is a potent, selective activator of the human melanocortin 1 receptor (MC1R), a G-protein-coupled receptor involved in skin pigmentation, inflammation regulation, and UV response. By stimulating MC1R, this agonist enhances melanin production, providing photoprotective effects and potential therapeutic benefits for conditions like vitiligo or UV-induced skin damage. It is widely used in dermatological and pharmacological research to explore melanocortin signaling pathways. hMC1R Agonist 1 also aids in studying receptor selectivity, intracellular signaling, and developing treatments targeting pigmentation disorders and inflammatory skin diseases.