For research use only. Not for therapeutic Use.
HKPerox-1 (Cat No.: I045483) is a selective fluorescent probe designed for the detection of hydrogen peroxide (H₂O₂) in biological systems. Upon reacting with H₂O₂, it undergoes a specific chemical transformation that generates a strong fluorescence signal, enabling real-time and sensitive monitoring. Widely used in oxidative stress research, HKPerox-1 helps study H₂O₂’s role in cell signaling, metabolism, and disease pathogenesis. Its high selectivity, fast response time, and compatibility with live-cell imaging make it valuable for investigating redox biology, inflammatory processes, and oxidative damage in various disease models.
CAS Number | 2240163-05-5 |
Synonyms | (4-formyl-3-hydroxyphenyl)methyl N-[6′-[(4-formyl-3-hydroxyphenyl)methoxycarbonyl-methylamino]-3-oxospiro[2-benzofuran-1,9′-xanthene]-3′-yl]-N-methylcarbamate |
Molecular Formula | C40H30N2O11 |
Purity | ≥95% |
InChI | InChI=1S/C40H30N2O11/c1-41(38(48)50-21-23-7-9-25(19-43)33(45)15-23)27-11-13-31-35(17-27)52-36-18-28(42(2)39(49)51-22-24-8-10-26(20-44)34(46)16-24)12-14-32(36)40(31)30-6-4-3-5-29(30)37(47)53-40/h3-20,45-46H,21-22H2,1-2H3 |
InChIKey | WOSPPMBMPHNEFP-UHFFFAOYSA-N |
SMILES | CN(C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(C)C(=O)OCC5=CC(=C(C=C5)C=O)O)C6=CC=CC=C6C(=O)O3)C(=O)OCC7=CC(=C(C=C7)C=O)O |
Reference | [1]. Trends Cell Biol. 2007 Sep;17(9):422-7. doi: 10.1016/j.tcb.2007.07.009. Epub 2007 Sep 4. [2]. Ye S, et, al. Tandem Payne/Dakin Reaction: A New Strategy for Hydrogen Peroxide Detection and Molecular Imaging. Angew Chem Int Ed Engl. 2018 Aug 6;57(32):10173-10177. |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |