HKOH-1r

• CAT Number: I045005
• CAS Number: 2138472-08-7
• Molecular Formula: C33H21Cl2I2NO11
• Molecular Weight: 938.28
• Purity: ≥95%
• Synonyms: 2′,7′-dichloro-3′-hydroxy-6′-(4-hydroxy-3,5-diiodophenoxy)spiro[2-benzofuran-3,9′-xanthene]-1-one;methyl 2-[acetyl-(2-methoxy-2-oxoethyl)amino]acetate
• IUPAC Name: 2',7'-dichloro-3'-hydroxy-6'-(4-hydroxy-3,5-diiodophenoxy)spiro[2-benzofuran-3,9'-xanthene]-1-one;methyl 2-[acetyl-(2-methoxy-2-oxoethyl)amino]acetate
• InChI: InChI=1S/C26H12Cl2I2O6.C8H13NO5/c27-16-7-14-21(9-20(16)31)35-22-10-23(34-11-5-18(29)24(32)19(30)6-11)17(28)8-15(22)26(14)13-4-2-1-3-12(13)25(33)36-26;1-6(10)9(4-7(11)13-2)5-8(12)14-3/h1-10,31-32H;4-5H2,1-3H3
• InChIKey: VHPOZCLVPZPUPA-UHFFFAOYSA-N
• SMILES: CC(=O)N(CC(=O)OC)CC(=O)OC.C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)OC6=CC(=C(C(=C6)I)O)I)O)Cl

HKOH-1r（Cat No.:I045005）is a ratiometric fluorescent probe specifically designed for the selective detection of hypochlorous acid (HOCl) in biological systems. Featuring a dual-emission fluorophore scaffold, HKOH-1r undergoes a measurable shift in fluorescence intensity ratios upon reaction with HOCl, allowing precise and quantitative imaging in live cells and tissues. Its high selectivity, fast response, and low cytotoxicity make it ideal for monitoring oxidative stress and inflammation-related processes. HKOH-1r is widely used to investigate HOCl’s role in immune responses, redox signaling, and pathological conditions such as infection, cancer, and cardiovascular disease.