For research use only. Not for therapeutic Use.
HJC0197（Cat No.:I007210）is a small-molecule inhibitor identified as a modulator of the STAT3 signaling pathway, a key regulator of cell proliferation, survival, and immune responses. By disrupting STAT3 activity, HJC0197 suppresses tumor growth, angiogenesis, and immune evasion, making it a promising compound for cancer research. Preclinical studies highlight its potential in targeting STAT3-driven malignancies and overcoming resistance to conventional therapies. Beyond oncology, it also provides value in studying inflammation and autoimmune disorders where STAT3 is dysregulated. HJC0197 serves as a versatile research tool in molecular pharmacology.
| CAS Number | 1383539-73-8 |
| Synonyms | 4-cyclopentyl-2-[(2,5-dimethylphenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile |
| Molecular Formula | C19H21N3OS |
| Purity | ≥95% |
| IUPAC Name | 4-cyclopentyl-2-[(2,5-dimethylphenyl)methylsulfanyl]-6-oxo-1H-pyrimidine-5-carbonitrile |
| InChI | InChI=1S/C19H21N3OS/c1-12-7-8-13(2)15(9-12)11-24-19-21-17(14-5-3-4-6-14)16(10-20)18(23)22-19/h7-9,14H,3-6,11H2,1-2H3,(H,21,22,23) |
| InChIKey | QLLWRTHDHRGHQZ-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1)C)CSC2=NC(=C(C(=O)N2)C#N)C3CCCC3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
