HIV-1 inhibitor-48

• CAT Number: R051574
• CAS Number: 374067-85-3
• Molecular Formula: C19H16BrN5
• Molecular Weight: 394.27
• Purity: ≥95%
• Synonyms: 4-[[4-(4-bromo-2,6-dimethylanilino)pyrimidin-2-yl]amino]benzonitrile
• InChI: InChI=1S/C19H16BrN5/c1-12-9-15(20)10-13(2)18(12)24-17-7-8-22-19(25-17)23-16-5-3-14(11-21)4-6-16/h3-10H,1-2H3,(H2,22,23,24,25)
• InChIKey: MKODFMNTDYAPSG-UHFFFAOYSA-N
• SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)Br

HIV-1 Inhibitor-48 (Cat No.: R051574) is a small-molecule compound designed to block key stages of the HIV-1 replication cycle, such as viral entry, reverse transcription, integration, or protease activity. While the specific target of inhibitor-48 may vary depending on its structure, compounds in this class typically aim to reduce viral load and prevent infection of host cells. HIV-1 Inhibitor-48 is used in antiviral research to evaluate new therapeutic strategies, particularly in drug-resistant strains, and supports the development of next-generation HIV treatments.

Reference

[1]. Ludovici DW, et al. Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2235-9.
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