Hh-Ag1.5

• CAT Number: R030630
• CAS Number: 612542-14-0
• Molecular Formula: C28H26ClF2N3OS
• Molecular Weight: 526.04
• Purity: ≥95%
• Synonyms: 3-chloro-4,7-difluoro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide
• InChI: InChI=1S/C28H26ClF2N3OS/c1-32-20-5-7-21(8-6-20)34(16-17-3-2-4-19(15-17)18-11-13-33-14-12-18)28(35)27-25(29)24-22(30)9-10-23(31)26(24)36-27/h2-4,9-15,20-21,32H,5-8,16H2,1H3
• InChIKey: RXZDWPYJFCAZCW-UHFFFAOYSA-N
• SMILES: CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=C(C=CC(=C5S4)F)F)Cl

Hh-Ag1.5（Cat No.:R030630）is a synthetic small-molecule agonist of the Hedgehog (Hh) signaling pathway, which plays a central role in embryonic development, stem cell regulation, and tissue repair. By binding to and activating Smoothened (SMO), Hh-Ag1.5 stimulates downstream signaling, leading to the transcription of Hedgehog target genes. This compound is widely used in developmental biology, cancer research, and regenerative medicine studies to investigate pathway activation and its biological consequences. Its ability to mimic endogenous Hedgehog ligands makes it a useful tool for dissecting signaling mechanisms and therapeutic applications.