For research use only. Not for therapeutic Use.
hGPR91 antagonist 3（Cat No.:I043971）is a small-molecule compound designed to selectively inhibit the human GPR91 receptor, a G protein-coupled receptor (GPCR) involved in various physiological processes, including regulation of immune response and inflammation. GPR91 is activated by succinate, a key metabolic intermediate, and plays a role in conditions such as metabolic disorders, cardiovascular diseases, and cancer. By blocking GPR91 activation, hGPR91 antagonist 3 may help modulate these pathways, offering potential therapeutic benefits in diseases driven by abnormal succinate signaling. The compound is under investigation for its efficacy in preclinical models targeting inflammation and metabolic diseases.
| CAS Number | 1314796-31-0 |
| Synonyms | N-[[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide |
| Molecular Formula | C23H18F4N4O2 |
| Purity | ≥95% |
| IUPAC Name | N-[[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide |
| InChI | InChI=1S/C23H18F4N4O2/c24-19-9-7-15(11-18(19)23(25,26)27)20-12-17(33-31-20)13-29-21(32)5-1-4-16-8-6-14-3-2-10-28-22(14)30-16/h2-3,6-12H,1,4-5,13H2,(H,29,32) |
| InChIKey | SWKGPCNQBPGWNX-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(N=C1)N=C(C=C2)CCCC(=O)NCC3=CC(=NO3)C4=CC(=C(C=C4)F)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
