Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one

• CAT Number: L030392
• CAS Number: 1000577-63-8
• Molecular Formula: C7H12N2O
• Molecular Weight: 140.18
• Purity: ≥95%
• IUPAC Name: 2,3,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-4-one
• InChI: InChI=1S/C7H12N2O/c10-7-5-8-4-6-2-1-3-9(6)7/h6,8H,1-5H2
• InChIKey: HAAZJWVQKLGNDT-UHFFFAOYSA-N
• SMILES: C1CC2CNCC(=O)N2C1

Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one（Cat No.:L030392）is a bicyclic nitrogen-containing heterocycle composed of a fused pyrrolidine and pyrazinone ring system, with a keto group at the 4-position. This compound is often regarded as a diketopiperazine (DKP) derivative, which are known for their stability, rigidity, and role as scaffolds in drug design and peptidomimetics. It is formed via cyclization of dipeptides and serves as a key intermediate in the synthesis of bioactive molecules, natural product analogs, and pharmaceuticals. Its conformational constraint enhances binding specificity in medicinal chemistry and structure-based drug design.