<p>
HERNANDEZINE(cas 6681-13-6) is probably a calcium antagonist, a platelet aggregation inhibitor an anti-inflammatory and an analgesic.
</p>
<br />
Bisbenzylisoquinoline alkaloid<!–C<sub>39</sub>H<sub>44</sub>N<sub>2</sub>O<sub>7</sub>–>, from plants of the <i>Thalictrum</i> genus, Ranunculaceae.<br />
<p>
It inhibits rat platelet aggregation induced by collagen, ADP, A23187 and arachidonic acid and inhibits A23187-induced concentration increase of cytosolic free calcium in human platelet.
</p>
<br />
| Catalog Number | T000065 |
| CAS Number | 6681-13-6 |
| Molecular Formula | C39H44N2O7 |
| Purity | ≥95% |
| Solubility | In chloroform; Not well in ethanol, methanol |
| Storage | Store at +4°C, in dark place. |
| InChI | InChI=1S/C39H44N2O7/c1-40-16-14-25-21-32(43-4)34-22-28(25)29(40)18-23-8-11-26(12-9-23)47-33-20-24(10-13-31(33)42-3)19-30-35-27(15-17-41(30)2)36(44-5)38(45-6)39(46-7)37(35)48-34/h8-13,20-22,29-30H,14-19H2,1-7H3/t29-,30-/m0/s1 |
| InChIKey | FUZMQNZACIFDBL-KYJUHHDHSA-N |
| SMILES | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(CCN6C)C(=C(C(=C7O3)OC)OC)OC)OC)OC |
| Reference | – Shu-Hua Chen et al., /Calcium antagonists from traditional Chinese herbs./ Drug News and Perspectives (1990). 3(7):425-428<br /> |
