HBC620(Cat No.:I045895)is a selective small-molecule inhibitor of casein kinase 2 (CK2), a serine/threonine protein kinase that regulates critical cellular processes, including proliferation, survival, DNA repair, and stress signaling. By blocking CK2 activity, HBC620 interferes with phosphorylation networks that support tumor growth and resistance, making it highly relevant in cancer biology research. It has been utilized to study CK2-driven pathways in oncogenesis, apoptosis, and inflammation, helping to validate CK2 as a therapeutic target. HBC620 serves as a valuable chemical probe for drug discovery and signal transduction studies.