HBC599（Cat No.:I045894）is a research-grade small-molecule inhibitor developed to selectively target casein kinase 2 (CK2), a ubiquitous serine/threonine kinase regulating pathways linked to cell proliferation, apoptosis, DNA repair, and stress responses. By suppressing CK2 activity, HBC599 alters phosphorylation cascades that contribute to oncogenesis and inflammatory signaling. It has been applied in studies of tumor biology, kinase regulation, and therapeutic target validation, providing insights into CK2’s role as a master regulator of cellular homeostasis. HBC599 serves as a valuable probe for drug discovery and cancer research.