For research use only. Not for therapeutic Use.
HBC514（Cat No.:I045893）is a small-molecule research compound identified as a selective inhibitor of casein kinase 2 (CK2), a serine/threonine protein kinase involved in regulating cell survival, proliferation, and stress responses. By blocking CK2 activity, HBC514 disrupts phosphorylation events that drive oncogenic signaling, making it useful for studying cancer biology and targeted therapy development. It has also been applied in exploring CK2’s role in apoptosis, DNA repair, and inflammatory pathways. As a chemical probe, HBC514 provides researchers with a tool to dissect CK2-mediated signaling networks and therapeutic opportunities.
| CAS Number | 2530161-67-0 |
| Synonyms | 4-[(Z)-1-cyano-2-[4-[2-(dimethylamino)ethyl-methylamino]phenyl]ethenyl]benzonitrile |
| Molecular Formula | C21H22N4 |
| Purity | ≥95% |
| IUPAC Name | 4-[(Z)-1-cyano-2-[4-[2-(dimethylamino)ethyl-methylamino]phenyl]ethenyl]benzonitrile |
| InChI | InChI=1S/C21H22N4/c1-24(2)12-13-25(3)21-10-6-17(7-11-21)14-20(16-23)19-8-4-18(15-22)5-9-19/h4-11,14H,12-13H2,1-3H3/b20-14+ |
| InChIKey | BCLYGBLOTWSFBR-XSFVSMFZSA-N |
| SMILES | CN(C)CCN(C)C1=CC=C(C=C1)/C=C(\C#N)/C2=CC=C(C=C2)C#N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
