For research use only. Not for therapeutic Use.
Harpagoside（Cat No.:R015015）is an iridoid glycoside primarily isolated from Harpagophytum procumbens (devil’s claw), a traditional medicinal plant. It is best known for its potent anti-inflammatory and analgesic properties, making it valuable in managing arthritis, back pain, and musculoskeletal disorders. Mechanistically, Harpagoside inhibits pro-inflammatory mediators such as TNF-α, IL-1β, and COX-2, while modulating NF-κB and MAPK pathways. It also exhibits antioxidant activity, protecting cells from oxidative stress. With its strong pharmacological profile, Harpagoside remains an important natural compound in research on inflammation, pain, and degenerative diseases.
| CAS Number | 19210-12-9 |
| Synonyms | [(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate |
| Molecular Formula | C24H30O11 |
| Purity | ≥95% |
| IUPAC Name | [(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate |
| InChI | InChI=1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1 |
| InChIKey | KVRQGMOSZKPBNS-FMHLWDFHSA-N |
| SMILES | C[C@@]1(C[C@H]([C@]2([C@@H]1[C@@H](OC=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O)OC(=O)/C=C/C4=CC=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
