H3K27(Me3) (15-34)

• CAT Number: P000335
• Molecular Formula: C87H157N30O25
• Molecular Weight: 2023.40
• Purity: ≥95%

H3K27(Me3) (15-34)（Cat No.:P000335）is a synthetic histone H3 peptide spanning amino acids 15–34, with lysine 27 trimethylated. This modification is a hallmark of transcriptional repression and facultative heterochromatin, deposited by the Polycomb repressive complex 2 (PRC2). It plays a critical role in developmental gene silencing, X-chromosome inactivation, and maintenance of stem cell identity. The peptide is widely used in epigenetics research to study histone–protein interactions, enzyme recognition, and chromatin remodeling mechanisms. H3K27(Me3) (15-34) provides a precise tool for dissecting repressive epigenetic signaling and transcriptional regulation.