For research use only. Not for therapeutic Use.
H2N-PEG2-CH2COOtBu（Cat No.:I044506）is a bifunctional polyethylene glycol (PEG)-based linker molecule featuring an amino (H2N) group on one end and a tert-butyl ester (COOtBu)–protected carboxylic acid on the other. The PEG2 spacer (diethylene glycol) provides flexibility, water solubility, and reduced steric hindrance, facilitating bioconjugation and drug delivery applications. The amino group enables coupling to electrophilic functional groups (e.g., activated esters), while the tert-butyl ester protects the carboxyl group during synthesis and can be removed under mild acidic conditions. This linker is widely used in peptide synthesis, PROTAC design, and targeted therapeutic development.
| CAS Number | 1122484-77-8 |
| Synonyms | tert-butyl 2-[2-(2-aminoethoxy)ethoxy]acetate |
| Molecular Formula | C10H21NO4 |
| Purity | ≥95% |
| IUPAC Name | tert-butyl 2-[2-(2-aminoethoxy)ethoxy]acetate |
| InChI | InChI=1S/C10H21NO4/c1-10(2,3)15-9(12)8-14-7-6-13-5-4-11/h4-8,11H2,1-3H3 |
| InChIKey | WFBRWOZVLSLRSZ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)COCCOCCN |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
