Gypenoside LXXV

• CAT Number: I044881
• CAS Number: 110261-98-8
• Molecular Formula: C42H72O13
• Molecular Weight: 785.01
• Purity: ≥95%
• Synonyms: (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6S)-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,55-37-35(51)33(49)31(47)25(54-37)20-52-36-34(50)32(48)30(46)24(19-43)53-36)22-11-16-41(7)29(22)23(44)18-27-39(5)15-13-28(45)38(3,4)26(39)12-17-40(27,41)6/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36+,37-,39-,40+,41+,42-/m0/s1
• InChIKey: YIYRCZFIJNGYOG-QINBLQPGSA-N
• SMILES: CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O)O)O)C

Gypenoside LXXV（Cat No.:I044881）is a dammarane-type triterpenoid saponin isolated from Gynostemma pentaphyllum, a traditional medicinal herb known as “Jiaogulan.” Structurally, it features multiple sugar moieties attached to a hydrophobic triterpene backbone, contributing to its amphiphilic nature and bioactivity. Gypenoside LXXV is recognized for its potent antioxidant, anti-inflammatory, neuroprotective, and antitumor effects. It modulates cellular pathways such as AMPK and NF-κB, supporting metabolic health, immune regulation, and cancer suppression. Due to its broad pharmacological potential, it is widely studied in integrative medicine and functional food research for health-promoting applications.