Guanoxabenz hydrochloride（Cat No.:I028460）is an α2-adrenergic receptor agonist and antihypertensive agent structurally related to guanabenz. It functions by stimulating central α2-adrenoceptors, which leads to reduced sympathetic outflow and lowered blood pressure. Additionally, guanoxabenz has been studied for its potential neuroprotective and anti-inflammatory effects, particularly through its interaction with cellular stress response pathways such as the unfolded protein response (UPR). The hydrochloride form enhances its solubility and stability for experimental use. It is commonly employed in pharmacological research focused on cardiovascular regulation, neurodegenerative diseases, and metabolic disorders.