For research use only. Not for therapeutic Use.
Guanidine thiocyanate, ultrapure (Cat No.: R001544) is a strong chaotropic agent commonly used in molecular biology for cell lysis and nucleic acid extraction. Its ability to denature proteins and inactivate RNases and DNases makes it ideal for isolating high-quality RNA and DNA. The ultrapure grade ensures minimal contamination, which is essential for sensitive applications like RT-PCR, qPCR, and next-generation sequencing. Guanidine thiocyanate is often used in combination with phenol or silica-based columns in commercial RNA extraction kits for consistent, reliable results.
| CAS Number | 593-84-0 |
| Molecular Formula | CN3H5 •HSCN |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Storage | 2-8 °C |
| IUPAC Name | guanidine;thiocyanic acid |
| InChI | InChI=1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H |
| InChIKey | ZJYYHGLJYGJLLN-UHFFFAOYSA-N |
| SMILES | C(#N)S.C(=N)(N)N |
| Reference | <p>Roberts, P. L. /Virus Inactivation by Protein Denaturants Used in Affinity Chromatography./ <em>Biologicals: Journal of the International Association of Biological Standardization</em> 35.4 (2007): 343-47. <em>Ncbi.gov</em>. 24 May 2007. Web. 12 Sept. 2012.</p></span></p> |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
