For research use only. Not for therapeutic Use.
Guaifenesin (Cat No.: A000410) is an expectorant commonly used to relieve chest congestion in conditions like the common cold, bronchitis, and other respiratory tract infections. It works by thinning and loosening mucus in the airways, making it easier to cough up and clear from the lungs. Guaifenesin is available in oral tablets, syrups, and extended-release forms. It is generally well-tolerated, with mild side effects such as nausea, dizziness, or headache. Adequate hydration enhances its effectiveness. It is often combined with cough suppressants.
CAS Number | 93-14-1 |
Synonyms | 93-14-1; Guaiphenesin; Glycerol guaiacolate; Guaiphenesine; Guaiacol glyceryl ether |
Molecular Formula | C10H14O4 |
Purity | ≥95% |
Target | Mucin |
Storage | -20°C |
IUPAC Name | 3-(2-methoxyphenoxy)propane-1,2-diol |
InChI | 1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3 |
InChIKey | HSRJKNPTNIJEKV-UHFFFAOYSA-N |
SMILES | COC1=CC=CC=C1OCC(CO)O |
Reference | 1: Aoki M, Wakuno A, Kushiro A, Mae N, Kakizaki M, Nagata SI, Ohta M. Evaluation 2: Septimus EJ, Albrecht HH, Solomon G, Shea T, Guenin EP. Extended-Release <br> 4: Deng S, Huang W, Ni X, Zhang M, Lu H, Wang Z, Hu J, Zhu X, Qiu C, Shang D, 5: Kolbach-Mandel AM, Mandel NS, Cohen SR, Kleinman JG, Ahmed F, Mandel IC, 6: Shabbir A, Shamsi S, Shahzad M, Butt HI, Aamir K, Iqbal J. Evaluation of 7: Knych HK, Stanley SD, Benson D, Arthur RM. Pharmacokinetics of guaifenesin 8: Melegari C, Bertoni S, Genovesi A, Hughes K, Rajabi-Siahboomi AR, Passerini N, 9: Thompson GA, Solomon G, Albrecht HH, Reitberg DP, Guenin E. Guaifenesin 10: Yehia AM, Mohamed HM. Chemometrics resolution and quantification power |
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