1. Home
  2. Product
  3. Inhibitors/Agonists
  4. RIP kinase
  5. GSK963

GSK963 - CAS 2049868-46-2

GSK’963 (Cat No.:I019551) is a chiral small molecule inhibitor of RIP1 kinase (RIPK1), with IC50 value of 29 nM in FP binding assay. It is more than 10,000-fold selective for RIP1 over 339 other kinases. GSK’963 can maintain a certain blood concentration and inhibit 90% of RIP1 activity, compared with Nec-1, the duration of action is longer.

Catalog Number: I019551

CAS Number: 2049868-46-2

Molecular Formula: C₁₄H₁₈N₂O

Molecular Weight:230.31

Purity: ≥95%

Online inquiry

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C₁₄H₁₈N₂O
Molecular Weight230.31
Purity≥95%
StorageStore at -20°C

Computed Descriptor

IUPAC Name2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one
InChIInChI=1S/C14H18N2O/c1-14(2,3)13(17)16-12(9-10-15-16)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3/t12-/m0/s1
InChIKeyNJQVSLWJBLPTMD-LBPRGKRZSA-N
SMILESCC(C)(C)C(=O)N1C(CC=N1)C2=CC=CC=C2