GSK264220A（Cat No.:I007095）is a selective inhibitor of the transient receptor potential vanilloid 4 (TRPV4) ion channel, which is involved in various physiological processes including mechanosensation, osmoregulation, and inflammation. By blocking TRPV4 activity, GSK264220A reduces calcium influx in response to osmotic and mechanical stimuli, making it a valuable tool in the study of pain, edema, respiratory disorders, and cardiovascular disease. It is widely used in preclinical models to investigate TRPV4’s role in cellular signaling and tissue homeostasis. GSK264220A supports the development of novel therapies targeting TRPV4-associated pathologies.