For research use only. Not for therapeutic Use.
GSK1521498 free base（Cat No.:I007069）is a potent and selective μ-opioid receptor (MOR) antagonist developed to study reward circuitry and addictive behaviors. By blocking MOR signaling, it reduces opioid-mediated reinforcement and modulates hedonic responses, making it valuable in addiction, obesity, and neuropsychiatric research. Preclinical and clinical investigations suggest GSK1521498 may help attenuate compulsive eating and drug-seeking behaviors. Its free base form offers flexibility in experimental use. As a research tool, GSK1521498 enables exploration of opioid receptor biology and therapeutic strategies targeting addiction and behavioral disorders.
| CAS Number | 1007573-18-3 |
| Synonyms | N-[[2,6-difluoro-4-[3-(1H-1,2,4-triazol-5-yl)phenyl]phenyl]methyl]-2,3-dihydro-1H-inden-2-amine |
| Molecular Formula | C24H20F2N4 |
| Purity | ≥95% |
| IUPAC Name | N-[[2,6-difluoro-4-[3-(1H-1,2,4-triazol-5-yl)phenyl]phenyl]methyl]-2,3-dihydro-1H-inden-2-amine |
| InChI | InChI=1S/C24H20F2N4/c25-22-11-19(15-6-3-7-18(8-15)24-28-14-29-30-24)12-23(26)21(22)13-27-20-9-16-4-1-2-5-17(16)10-20/h1-8,11-12,14,20,27H,9-10,13H2,(H,28,29,30) |
| InChIKey | WIEDUMBCZQRGSY-UHFFFAOYSA-N |
| SMILES | C1C(CC2=CC=CC=C21)NCC3=C(C=C(C=C3F)C4=CC(=CC=C4)C5=NC=NN5)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
