GSK-3 Inhibitor XIII

• CAT Number: I043940
• CAS Number: 404828-14-4
• Molecular Formula: C18H15N5
• Molecular Weight: 301.35
• Purity: ≥95%
• Synonyms: N-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-5,6,7,8-tetrahydroquinazolin-4-amine
• IUPAC Name: N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
• InChI: InChI=1S/C18H15N5/c1-12-11-16(23-22-12)20-18-14-9-5-6-10-15(14)19-17(21-18)13-7-3-2-4-8-13/h2-11H,1H3,(H2,19,20,21,22,23)
• InChIKey: JYCUVOXSZBECAY-UHFFFAOYSA-N
• SMILES: CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=C4

GSK-3 Inhibitor XIII（Cat No.:I043940）is a selective small molecule inhibitor targeting glycogen synthase kinase-3 (GSK-3), an enzyme involved in key cellular processes like cell cycle regulation, apoptosis, and signal transduction. By inhibiting GSK-3, it modulates the Wnt/β-catenin pathway, making it a valuable tool in research on cancer, neurodegenerative diseases, and diabetes. GSK-3 Inhibitor XIII has been used to investigate potential therapeutic strategies for conditions where GSK-3 activity is dysregulated, including Alzheimer’s disease, bipolar disorder, and various types of cancer. It offers insight into GSK-3’s role in disease progression.