For research use only. Not for therapeutic Use.
GSHtracer (Cat No.: I045474) is a fluorescent probe designed for real-time detection and quantification of intracellular glutathione (GSH), the primary cellular antioxidant involved in redox homeostasis, detoxification, and signaling. It reacts selectively with GSH to produce a measurable fluorescence signal, enabling dynamic monitoring of GSH levels in live cells and tissues. GSHtracer is used in oxidative stress research, drug screening, and disease studies related to cancer, neurodegeneration, and inflammation. Its high sensitivity, selectivity, and compatibility with live-cell imaging make it valuable for redox biology investigations.
| CAS Number | 1479071-34-5 |
| Synonyms | (E)-2-cyano-N,N-dimethyl-3-(4-oxo-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-5-yl)prop-2-enamide |
| Molecular Formula | C21H21N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H21N3O3/c1-23(2)20(25)16(12-22)11-15-10-14-9-13-5-3-7-24-8-4-6-17(18(13)24)19(14)27-21(15)26/h9-11H,3-8H2,1-2H3/b16-11+ |
| InChIKey | YCXQIYZKBAKCHQ-LFIBNONCSA-N |
| SMILES | CN(C)C(=O)C(=CC1=CC2=CC3=C4C(=C2OC1=O)CCCN4CCC3)C#N |
| Reference | [1]. Eui Man Jeong, et al. Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function. Stem Cell Reports. 2018 Feb 13;10(2):600-614. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
