GRAVEOLINE - CAS 485-61-0

GRAVEOLINE(cas 485-61-0) is a CNS stimulant, convulsant and hypertensive.

Alkaloid, from plants of the Rutaceae family.
As CNS stimulant, it increases breath rhythm, reflex excitability and intensifies clinical cramps (tonic cramps).br>1 – 10 mg/kg increase arterial pressure by 5 – 20 mm Hg during 2 – 30 min.
1 – 3 – 5 mg/kg, on cats and dogs under anaesthesia, increase breath rhythm, which remains after decerebration, total excision of cerebellum and carotide ganglion block.
3 mg/kg and more, increase electric activity in the cortex and subcortex formations.
5 mg/kg remove completely the action of Thiopental sodium, Barbamil, Aminazine and Morphine on the bioelectrical activity of rabbit brain.
0.5 – 3mg/kg facilitate the conductivity of electric impulse in the downward activating system and stimulates the respiratory system of the reticulum formation of the caudal part of cat brain.

Catalog Number: T000120

CAS Number: 485-61-0

PubChem Substance ID:355170889

Molecular Formula: C17H13NO3

Molecular Weight:279.295

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms4(1H)-Quinolone,1-methyl-2-[3,4-(methylenedioxy)phenyl]- (6CI,7CI,8CI)

Property

Molecular Formula: C17H13NO3
Molecular Weight279.295
SolubilityIn chloroform and hot alcohol
Purity≥95%
StorageStore at +4°C, in dark place.

Computed Descriptor

IUPAC Name2-(1,3-benzodioxol-5-yl)-1-methylquinolin-4-one
InChIInChI=1S/C17H13NO3/c1-18-13-5-3-2-4-12(13)15(19)9-14(18)11-6-7-16-17(8-11)21-10-20-16/h2-9H,10H2,1H3
InChIKeyCOBBNRKBTCBWQP-UHFFFAOYSA-N
SMILESCN1C2=CC=CC=C2C(=O)C=C1C3=CC4=C(C=C3)OCO4