GPR88-IN-1

• CAT Number: I040547
• CAS Number: 714265-50-6
• Molecular Formula: C25H28N4O2
• Molecular Weight: 416.52
• Purity: ≥95%
• Synonyms: 4-(2-benzylanilino)-2-(cyclohexylmethylamino)pyrimidine-5-carboxylic acid
• InChI: InChI=1S/C25H28N4O2/c30-24(31)21-17-27-25(26-16-19-11-5-2-6-12-19)29-23(21)28-22-14-8-7-13-20(22)15-18-9-3-1-4-10-18/h1,3-4,7-10,13-14,17,19H,2,5-6,11-12,15-16H2,(H,30,31)(H2,26,27,28,29)
• InChIKey: XZFTUBCGJFWCHL-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)CNC2=NC=C(C(=N2)NC3=CC=CC=C3CC4=CC=CC=C4)C(=O)O

GPR88-IN-1(CAT: I040547) is a selective small-molecule inhibitor targeting G protein-coupled receptor 88 (GPR88), an orphan receptor predominantly expressed in the striatum of the brain. GPR88 is implicated in modulating dopaminergic and glutamatergic neurotransmission, and its dysregulation is associated with neuropsychiatric disorders such as schizophrenia, Parkinson’s disease, and addiction. GPR88-IN-1 enables precise investigation of GPR88 signaling pathways, offering insights into its physiological and pathological roles. This compound is a valuable pharmacological tool for neuroscience research, particularly in behavioral and functional studies related to motor control and cognitive processes. Ideal for in vitro and in vivo applications targeting central nervous system pathways.