For research use only. Not for therapeutic Use.
Gotistobart(CAT: I040385) is a fully human IgG1κ monoclonal antibody designed to target GITR ligand (GITRL), a key regulator of T cell co-stimulation and immune tolerance. By binding GITRL, Gotistobart modulates both effector and regulatory T cell responses, enhancing anti-tumor immunity while maintaining immune homeostasis. It is currently being evaluated in Phase I clinical trials for various solid tumors, demonstrating promising immune activation and a strong safety profile. Supplied at high purity, Gotistobart is ideal for advanced research in tumor immunology, immune checkpoint modulation, and translational studies focusing on costimulatory pathway-targeted therapies.
| CAS Number | 2226344-78-9 |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
