Gly-Gly-Gly-PEG4-azide

• CAT Number: I045187
• Molecular Formula: C16H31N7O7
• Molecular Weight: 433.46
• Purity: ≥95%
• Synonyms: 2-amino-N-[2-[[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]amino]-2-oxoethyl]acetamide
• InChI: InChI=1S/C16H31N7O7/c17-11-14(24)20-13-16(26)21-12-15(25)19-1-3-27-5-7-29-9-10-30-8-6-28-4-2-22-23-18/h1-13,17H2,(H,19,25)(H,20,24)(H,21,26)
• InChIKey: XKWKEPSEKGSYSV-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCN=[N+]=[N-])NC(=O)CNC(=O)CNC(=O)CN

Gly-Gly-Gly-PEG4-azide（Cat No.:I045187）is a versatile chemical linker composed of a triglycine peptide sequence attached to a PEG4 (tetraethylene glycol) spacer terminating with an azide group. The triglycine motif offers protease sensitivity or structural flexibility, while the PEG4 unit enhances solubility and reduces steric hindrance in conjugation reactions. The terminal azide enables bioorthogonal click chemistry, such as copper-catalyzed azide–alkyne cycloaddition (CuAAC), for site-specific labeling or bioconjugation. This reagent is widely used in chemical biology, proteomics, and drug delivery research for designing targeted probes, linkers, and functionalized biomolecules with controlled spacing and reactivity.