Glutamate dehydrogenase

• CAT Number: I042558
• CAS Number: 9001-46-1
• Purity: ≥95%

Glutamate dehydrogenase (Cat No.: I042558) is a mitochondrial enzyme that catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate and ammonia, linking amino acid metabolism with the citric acid cycle. It plays a crucial role in nitrogen balance and energy production, especially in the liver, kidney, and brain. GDH is allosterically regulated and sensitive to cellular energy states. It is used in clinical diagnostics and biochemical research, including studies on hyperinsulinism, metabolic regulation, and mitochondrial function in health and disease.

Reference

[1]. S A Robinson, et al. The role of glutamate dehydrogenase in plant nitrogen metabolism. Plant Physiol. 1991 Feb;95(2):509-16.
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