For research use only. Not for therapeutic Use.
Glucokinase Activator 3（Cat No.:I044058）is a selective small-molecule compound that enhances the activity of glucokinase (GK), a key enzyme in glucose sensing and metabolism primarily expressed in the liver and pancreatic β-cells. By increasing GK’s affinity for glucose and its catalytic efficiency, this activator boosts glucose utilization and insulin secretion, making it especially valuable in research on type 2 diabetes and metabolic disorders. Glucokinase Activator 3 supports investigations into glycemic control, β-cell function, and hepatic glucose metabolism, offering a promising therapeutic strategy for improving insulin sensitivity and maintaining glucose homeostasis.
| CAS Number | 1001417-92-0 |
| Synonyms | N-[4-(diethoxyphosphorylmethyl)-1,3-thiazol-2-yl]-3-[(2S)-1-methoxypropan-2-yl]oxy-5-(4-methylsulfonylphenoxy)benzamide |
| Molecular Formula | C26H33N2O9PS2 |
| Purity | ≥95% |
| IUPAC Name | N-[4-(diethoxyphosphorylmethyl)-1,3-thiazol-2-yl]-3-[(2S)-1-methoxypropan-2-yl]oxy-5-(4-methylsulfonylphenoxy)benzamide |
| InChI | InChI=1S/C26H33N2O9PS2/c1-6-34-38(30,35-7-2)16-20-17-39-26(27-20)28-25(29)19-12-22(36-18(3)15-33-4)14-23(13-19)37-21-8-10-24(11-9-21)40(5,31)32/h8-14,17-18H,6-7,15-16H2,1-5H3,(H,27,28,29)/t18-/m0/s1 |
| InChIKey | OQUMCVQSAWPKMT-SFHVURJKSA-N |
| SMILES | CCOP(=O)(CC1=CSC(=N1)NC(=O)C2=CC(=CC(=C2)O[C@@H](C)COC)OC3=CC=C(C=C3)S(=O)(=O)C)OCC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
