For research use only. Not for therapeutic Use.
GLP-1(32–36)amide（Cat No.:I044239）is a short C-terminal fragment of the glucagon-like peptide-1 (GLP-1), comprising the amino acids 32 to 36 and ending with an amide group. Despite lacking the full receptor-binding region of native GLP-1, this pentapeptide has demonstrated bioactivity independent of the classical GLP-1 receptor, particularly in cardiovascular and metabolic contexts. It has been shown to enhance myocardial glucose uptake, reduce oxidative stress, and improve cardiac function in preclinical models. GLP-1(32–36)amide is a valuable research tool for exploring non-canonical pathways of GLP-1-derived peptide action in metabolic disease and cardioprotection.
| CAS Number | 1417302-71-6 |
| Synonyms | (2S)-6-amino-N-[2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]hexanamide |
| Molecular Formula | C25H50N10O5 |
| Purity | ≥95% |
| IUPAC Name | (2S)-6-amino-N-[2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]hexanamide |
| InChI | InChI=1S/C25H50N10O5/c1-14(2)12-16(27)22(38)35-20(15(3)4)24(40)34-18(8-5-6-10-26)23(39)32-13-19(36)33-17(21(28)37)9-7-11-31-25(29)30/h14-18,20H,5-13,26-27H2,1-4H3,(H2,28,37)(H,32,39)(H,33,36)(H,34,40)(H,35,38)(H4,29,30,31)/t16-,17-,18-,20-/m0/s1 |
| InChIKey | VCMIHDDYZTYYJC-JPLJXNOCSA-N |
| SMILES | CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
