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GLP-1(7-37) - CAS 106612-94-6


GLP-1(7-37) (CAS 106612-94-6) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37).

target: GLP-1 receptor

IC50:0.31 ± 0.01nM(Binding experiments with RIN T3 membranes)

EC50:0.9 ± 0.1nM(RIN T3 cells cyclic AMP Production)

In vitro: After ingestion of a meal, the truncated bioactive sequences GLP-1(7-37) is secreted by the L cells of the intestinal mucosa.it has EC50 of 0.9 ± 0.1nM when test the RIN T3 cells cyclic AMP production;Besides,it has IC50 of 0.31 ± 0.01nM for the binding experiments with RIN T3 membranes.

Catalog Number: P000029

CAS Number: 106612-94-6

Molecular Formula: C151H228N40O47

Molecular Weight:3355.67

Purity: 98.0%

Appearance:Solid powder

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* For research use only. Not for human or veterinary use.

Synonym

SynonymsGLP-1 (7-37) peptide; Glucagon like Peptide-1 (7-37) Acetate. Insulinotropin. Tglp-1.;His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly, tetracetate

Property

Molecular Formula: C151H228N40O47
Molecular Weight3355.67
Target:GLP-1 receptor
SolubilityH2O
Purity98.0%
StorageStore at -20°C

Computed Descriptor

SMILESO=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCC(N)